Adonis Raises $40 Million for AI-Powered Healthcare Revenue Management

Adonis, an artificial intelligence (AI) orchestration platform for healthcare revenue cycle management, has raised $40 million.

The Series C round, announced Wednesday (March 25), brings Adonis’ total funding to more than $95 million since it was founded in 2022.

“The announcement comes at an inflection point for the healthcare industry,” the company said in a news release. “Recent policy changes, including the passage of the One Big Beautiful Bill, have reshaped Medicaid and ACA subsidies, increasing the number of uninsured and self-pay patients while adding complexity to reimbursement requirements.

With denial rates climbing and payer policies evolving, revenue cycle teams face pressure to navigate an increasingly complicated reimbursement landscape.

The Adonis platform, the company said, employs a mix of intelligence and AI agent products that monitor and detect revenue cycle issues, suggest tailored actions and autonomously progress claims to resolution.

“Healthcare organizations can now level the playing field with payers, stabilize and increase revenue, and reduce the operational burden on staff,” the release added.

As PYMNTS wrote earlier this week, healthcare continues to be among the most fruitful areas for agentic AI.

That report gave the example of Dermatology Partners, a large dermatology group with 80 providers across 41 locations, which has turned to agentic AI to handle a heavy flow of patient phone calls, which can come in at a rate of 2,000 to 4,000 per day.

“They turned to a voice-based AI system that could speak directly with patients, schedule appointments and work inside the group’s existing practice management platform,” PYMNTS wrote, with the practice choosing “a voice-first approach because many patients are older and may be less comfortable with text-based tools.”

AI is also moving into the financial mechanics of the multi-billion dollar healthcare payment space, PYMNTS wrote in another recent report. Hospitals are using the technology to maximize reimbursement, while insurers turn to AI to audit claims and challenge charges.

“The numbers on both sides reflect the amount at play. UnitedHealth Group projects AI could save it nearly $1 billion in 2026, while HCA Healthcare expects roughly $400 million in AI-driven cost savings, partly from automating revenue management,” PYMNTS wrote.

“On the other side of that ledger, Blue Cross Blue Shield has released an analysis suggesting that AI-enabled coding practices may be responsible for more than $2 billion in additional claims spending nationwide,” the report added.